Myocardial Perfusion Imaging by Combined 15O-H2O PET and MR (PREFER)
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Conditions
Details and patient eligibility
About
The trial will include 75 patients with evident or suspected ischemic heart disease refered to Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, for perfusion imaging by 15O-H2O PET/CT scan of the heart during rest and stress. Instead of the clinical scan participants will undergo perfusion imaging by 15O-H2O PET/MR.
The clinician will receive diagnostic information based on the 15O-H2O PET scan as if the patient had not participated in the study. As such, the study has no influence on the diagnostics or treatments of the patient.
Data from the scans will be used to compare 15O-H2O PET with cardiac MR for evaluation of myocardial perfusion.
Follow up will be done for up to 10 years in regards to major cardiovascular events in order to determine the prognostic value of the scan.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Refered for myocardial perfusion imaging by O15-H2O PET at Department of Nuclear Medicine & PET Centre, Aarhus University Hospital
- > 18 years of age
Exclusion criteria
- Allergic to adenosine
- Allergic to gadolinium
- Pregnancy
- Claustrophobia
- Severe Asthma
- Pacemaker or other ferro-magnetic implants
- GFR < 30
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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