Myocardial Salvage Assessed by Cardiovascular Magnetic Resonance - Impact on Outcome

University of Leipzig

Status: Completed

Conditions: ST-Elevation Myocardial Infarction

Treatments: Other: magnetic resonance imaging

Study type: Observational

Funder types: Other

Identifiers

NCT00952224

Leipzig MR 1

Details and patient eligibility

About

In acute myocardial infarction cardiovascular magnetic resonance imaging can retrospectively detect the myocardium at risk and the irreversible injury. This allows for quantifying the extent of salvaged myocardium after reperfusion as a potential strong end point for clinical trials and outcome. The aim of the present study is to determine the prognostic significance and determinants of myocardial salvage assessed by CMR in reperfused ST-elevation myocardial infarction (STEMI).

Enrollment: 267 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ST-elevation myocardial infarction < 12 hours
• primary percutaneous coronary intervention

Exclusion criteria

• previous myocardial infarction
• prior fibrinolysis
• contraindications to CMR at study entry (such as implanted pacemakers, defibrillators, claustrophobia or metallic intracranial implants)

Trial design

267 participants in 1 patient group

Acute myocardial infarction patients

Description:

Patients undergoing primary percutaneous coronary intervention in ST-elevation myocardial infarction plus magnetic resonance imaging

Treatment:

Other: magnetic resonance imaging