Myocardial Work for Prediction of Left Ventricular Remodeling in Patients With STEMI

Shanghai Jiao Tong University

Status: Completed

Conditions: ST-Segment Elevated Myocardial Infarction

Study type: Observational

Funder types: Other

Identifiers

NCT05107102

STEMI-myocardial work

Details and patient eligibility

About

The study intends to investigate the alteration of regional myocardial work in patients with acute anterior myocardial infarction underwent primary percutaneous coronary intervention (PCI), and compare the distribution of regional myocardial work in patients with/without early remodeling at acute phase and 3-month follow-up.

Enrollment: 98 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Anterior myocardial infarct (anterior myocardial infarct is defined as persistent chest pain for 30 mins at least, with ST-segment elevation of at least 0.2 mV in two or more contiguous precordial leads) within 12 hours after onsets of symptom;
• Left anterior descending (LAD) as culprit vessel, with TIMI 0-1 grade.

Exclusion criteria

• significant valvular disease;
• cardiomyopathy; l
• left bundle branch block;
• atrial fibrillation;
• previous myocardial infarction (MI);
• history of cardiac surgery;
• pacemaker implantation.

Trial design

98 participants in 2 patient groups

patients with LVR(left ventricular remodeling)

patients without LVR(left ventricular remodeling)