Myocellular Signalling in Skeletal Muscle

University of Copenhagen

Status: Completed

Conditions: Insulin Sensitivity; Exercise

Treatments: Drug: Insulin; Other: Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03203317

TIN-X

Details and patient eligibility

About

The study will investigate myocellular signalling in skeletal muscle after insulin-stimulation and exercise in healthy young men

Enrollment: 8 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy
• informed consent
• habitual training (2-5 h/week)
• VO2max of 40-60 ml/min/kg
• lean mass 55-65 kg

Exclusion criteria

• smoker
• allergy towards insulin
• chronic disease

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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8 participants in 2 patient groups

Insulin-stimulation

Experimental group

Description:

2 h insulin-clamp

Treatment:

Drug: Insulin

Exercise

Experimental group

Description:

10 min of maximal exercise

Treatment:

Other: Exercise