Myofascial Pain Syndrome and Dextrose Prolotherapy

Mustafa Kemal University

Status and phase: Unknown; Phase 4

Conditions: Efficacy of Dextrose Prolotherapy in Myofascial Pain Syndrome

Treatments: Drug: Injection of dextrose, local anesthetic and saline to the myofascial trigger point; Drug: Local anesthetic and saline injection to the myofascial trigger point

Study type: Interventional

Funder types: Other

Identifiers

NCT04941118

MustafaKUPMR-MPS

Details and patient eligibility

About

Myofascial pain syndrome is characterized by the presence of hypersensitive points called trigger points that cause pain, tenderness, spasm, stiffness, limitation of movement, weakness, taut band within the muscle, and pain reflected by pressing in a muscle group or a single muscle.

Prolotherapy is a regenerative treatment method in the treatment of chronic musculoskeletal pain, in which an irritating solution is injected, often hypertonic dextrose, into painful ligament and tendon attachments and adjacent joint spaces.

In this study, it was aimed to examine the effect of prolotherapy application on pain, neck range of motion and neck disability in women with myofascial pain syndrome.

Enrollment: 60 estimated patients

Sex: Female

Ages: 20 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 60 women aged 20-50 years with a diagnosis of myofascial pain syndrome

Exclusion criteria

• Cervical radiculopathy, cervical degeneration, neck surgery or trauma in the last year, injection history for myofascial pain syndrome in the last 6 months, cognitive impairment and fibromyalgia, rheumatoid arthritis, hypothyroidism, diabetes mellitus

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Control group

Sham Comparator group

Description:

Only saline and local anesthetic (lidocaine)

Treatment:

Drug: Local anesthetic and saline injection to the myofascial trigger point

Dextrose prolotherapy group

Active Comparator group

Description:

Dextrose, saline and local anesthetic (lidocaine)

Treatment:

Drug: Injection of dextrose, local anesthetic and saline to the myofascial trigger point