MyoSense- Automated Muscle Hypertonicity Classification System

Great Lakes NeuroTechnologies

Status: Completed

Conditions: Stroke; Dystonia; Cerebral Palsy

Study type: Observational

Funder types: Other; Industry; NIH

Identifiers

NCT02076581

1R43NS076052-01A1 (U.S. NIH Grant/Contract)

NS076052-1

Details and patient eligibility

About

It is often difficult to quantify and distinguish aspects of abnormal muscle tone due to neurological injury. This makes it difficult to evaluate therapies that aim to reduce the effects of abnormal muscle tone. This research study will evaluate the feasibility of a clinician worn device to capture and quantify features of spasticity and dystonia.

Enrollment: 53 patients

Sex: All

Ages: 5+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Presentation of dystonia and/or spasticity or, if in control group, no neurological injury nor abnormal muscle tone
• Over the age of five.

Exclusion criteria

• Intolerable pain with manipulation of the knee, ankle, wrist, or elbow
• Limited range of motion in the knee, ankle, wrist or elbow due to orthopedic injury or severe contraction.
• Cognitive impairment resulting in inability to provide informed consent or complete the protocol.
• Under the age of five.

Trial design

53 participants in 4 patient groups

Stroke

Description:

Ten individuals with chronic stroke and limb spasticity will be recruited.

Dystonia

Description:

Ten individuals with dystonic limbs and no spasticity will be recruited.

Cerebral Palsy

Description:

Ten individuals with Cerebral palsy with the potential for a mix of dystonic and spastic abnormal tone in their affected limbs will be recruited.

Neurologically normal

Description:

Thirty individuals without neurological injury that are age matched to the rest of the study population will be recruited.