N-3 Polyunsaturated Fatty Acids Enriched Chicken Meet and Cardiovascular Function

Josip Juraj Strossmayer University of Osijek

Status: Enrolling

Conditions: n-3 Polyunsaturated Fatty Acids

Treatments: Dietary Supplement: N-3 PUFAs Chicken Meet; Dietary Supplement: Regular Chicken Meet

Study type: Interventional

Funder types: Other

Identifiers

NCT05725486

2158614622108

Details and patient eligibility

About

Evidence from multiple experimental, epidemiological, and clinical studies indicate that n-3 polyunsaturated fatty acids (n-3 PUFAs) may exert their cardiovascular (CV) protective effect, at least in part, by improving vascular endothelium-dependent function. Previously, the investigators demonstrated the significant beneficiary effect of consumption of n-3 PUFA-enriched hen eggs on microvascular endothelium-dependent reactivity, even in young healthy individuals.

The hypothesis of this research is that the consumption of n-3 PUFAs in the form of functionally enriched chicken meet has a beneficial effect on vascular reactivity measured in different vascular beds, and the lipid profile with a positive effect on the reduction of oxidative stress and inflammatory response in healthy sedentary individuals.

The main goal of this study is to investigate the influence of n-3 PUFAs functionally enriched chicken meet on vascular and endothelial function in a population of healthy young subjects and active athletes.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 39 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• young healthy sedentary individuals - did not perform regular physical activities for at least 12 months before conducting the study
• young healthy active athletes - have a minimum of 5 training sessions per week (mainly endurance training) for at least 12 months prior to conducting the study

Exclusion criteria

• smoking
• hypertension
• coronary disease
• diabetes
• hyperlipidemia
• kidney damage
• cerebrovascular and peripheral artery diseases
• and any other disease that could have an impact on vascular and endothelial function

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

50 participants in 2 patient groups

n-3 PUFA

Experimental group

Description:

Intake of n-3 PUFAs enriched chicken meet for three weeks

Treatment:

Dietary Supplement: N-3 PUFAs Chicken Meet

Control

Experimental group

Description:

Intake of regular chicken meet for three weeks

Treatment:

Dietary Supplement: Regular Chicken Meet