NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED

Seoul National University

Status and phase: Unknown; Phase 4

Conditions: Chronic Renal Failure

Treatments: Drug: NAC Bicarbonate

Study type: Interventional

Funder types: Other

Identifiers

NCT00501475

06-2006-084

Details and patient eligibility

About

The purpose of this study is to evaluate the effect of NAC or sodium bicarbonate in preventing the aggravation of renal function in chronic renal failure when enhanced computed tomography scan is checked in emergency room.

Full description

CIN is frequent in CRF patients. However most studies about CIN has been focusing on elective PCI patients. There is no study that the NAC nor sodium bicarbonate would help in preventing CIN in CRF patients who need enhanced CT scan in ED.

Our intention was to investigate the effect of NAC or sodium bicarbonate in preventing the aggravation of renal function in chronic renal failure when enhanced computed tomography scan is checked in emergency room.

Sex: All

Ages: 15+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• CRF patients who need enhanced CT scan

Exclusion criteria

• less than 15 years old
• hypersensitivity to NAC
• on dialysis
• no consent from patient or next of kin

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind