Nailfold Capillaroscopic Assessment in Pediatric Uveitis Patients

Assiut University

Status: Completed

Conditions: Uveitis

Study type: Observational

Funder types: Other

Identifiers

NCT06070935

Nailfold capillaroscopy

Details and patient eligibility

About

Pediatric uveitis accounts for 5-10% of uveitis cases. it may be infectious or noninfectious in etiology. The etiology of noninfectious uveitis may be autoimmune. The most common causes of pediatric uveitis are idiopathic and juvenile idiopathic arthritis-associated uveitis. Uveitis morbidities in pediatric patients include cataract, glaucoma, and amblyopia. Pediatric uveitis may be accopanied by involvement of the ocular vasculature, such as retinal vasculitis. We hypothesize that there are differences in systemic microcirculation between pediatric uveitis patients and healthy pediatric controls.

Full description

The systemic microcirculation will be investigated through nailfold capillaroscopic (NFC) assessment with noninfectious uveitis and healthy pediatric controls.

The NFC parameters are:

capillary density (number of capillaries per mm), dilated capillaries (apex of >20µm), avascular areas, the presence of microhemorrhages, and capillary morphology (normal, multiple crossings, tortuous, bushy, ramified, non-convex, or bizarre capillaries).

Enrollment: 46 patients

Sex: All

Ages: Under 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients with uveitis < 18 years old

Exclusion criteria

• infectious uveitis
• age > 18 years old

Trial design

46 participants in 2 patient groups

pediatric uveitis

Description:

pediatric uveitis patients \< 18 years old

healthy subjects

Description:

healthy subjects\< 18 years old