Nalmefene in Alcohol Dependence and Borderline Personality Disorder

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Status: Unknown

Conditions: Borderline Personality Disorder; Alcohol Use Disorder

Treatments: Drug: Nalmefene

Study type: Interventional

Funder types: Other

Identifiers

NCT02752503

IIBSP-NAL-2014-76

Details and patient eligibility

About

The objective is to study the effectiveness of Nalmefene in decreasing alcohol intake in subjects with alcohol use disorder and comorbid BPD.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Alcohol use disorder according to DSM 5
• Borderline personality disorder according to DSM 5
• CGI-BPD > 3
• Female have to use contraception

Exclusion criteria

• Other axis I disorders
• Severe organic disorder
• Pregnancy or breastfeeding
• Allergy to Nalmefene
• Subjects with Opioids use disorder or in treatment with opioid agonists

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Nalmafene

Experimental group

Treatment:

Drug: Nalmefene