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NANOTECH RCC Biomarkers

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The Washington University

Status

Completed

Conditions

Renal Cell Cancer
Renal Cell Carcinoma

Study type

Observational

Funder types

Other
NIH

Identifiers

NCT02923284
201601082
5R01CA141521 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The incidence of renal cell carcinoma (RCC or kidney cancer) in men exceeds that of pancreatic cancer or leukemia. In women, the incidence of RCC is similar to that of leukemia, ovarian, or pancreatic cancer; thus, RCC is significant health issue. This study focuses on identifying specific molecules [biomarkers] of RCC that can be used to develop a reliable low-cost screening method at the point of service. If successful, our method would provide a diagnostic test to distinguish benign kidney masses from malignant ones, eliminating the need to surgically remove a kidney with a benign tumor.

Enrollment

407 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients 18 years of age and older undergoing surgery. Patient samples are divided into 2 groups based on their surgery: Patients with an imaged renal mass, encompassing about 300 patients/year (about 1200 total) of both malignant (about 80-85% of time) and benign (about 15-20% of time), and patients with non-kidney cancers, encompassing about 6,000 patients/year (about 24,000 total),

Exclusion criteria

Age <18 years and prisoners.

Trial design

407 participants in 2 patient groups

Imaged renal mass cohort
Description:
Subjects undergoing surgery for an kidney tumor identified radiologically.
control cohort
Description:
Subjects undergoing surgery for any kind of cancer other than kidney.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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