Narrow Band Imaging Bronchoscopy During SARS-CoV2 Infection (SARS-CoV2-NBI)

Centre Hospitalier Universitaire, Amiens

Status

Active, not recruiting

Conditions

Narrow-band Imaging

Covid19

Bronchoscopy

Treatments

Other: NBI images and/or videos

Study type

Observational

Funder types

Other

Identifiers

NCT04884061

PI2021_843_0096

Details and patient eligibility

About

Vascular modifications have been described during SARS-CoV2 infection, especially a dilatation of the bronchial arteries. Within the airway wall, small branches of the bronchial arteries cross the muscle layer to develop a submucosal network. The Narrow Band Imaging technique is used during bronchoscopy to achieve a maximum contrast of vessels and the surrounding mucosa. Therefore, it enables to observe the microvessel structure and its distribution in the bronchial mucosa. The aim of this study is to describe the vasculature pattern of the bronchial tree during infection with SARS-CoV2.

Enrollment

27 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients who undergo bronchoscopy with image and/or videos recording of NBI aspect of the proximal bronchial tree (carina, right and left upper lobe).
Patients hospitalized with SARS-CoV2 infection proven by RT-PCR test
patients hospitalized with lower respiratory tract infections unrelated to SARS-CoV2 (RT-PCR negative for SARS-CoV2)
Patients who have had bronchoscopy performed as part of the assessment of a distal pulmonary nodule (RT-PCR negative for SARS-CoV2).

Exclusion criteria