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Narrowband UVB for Children With Moderate to Severe Atopic Eczema

R

Royal Victoria Infirmary

Status

Completed

Conditions

Moderate to Severe Atopic Eczema

Treatments

Radiation: Narrowband Ultraviolet B phototherapy

Study type

Observational

Funder types

Other

Identifiers

NCT01569906
7282 (Other Identifier)
4795

Details and patient eligibility

About

To assess prospectively, the response of moderate to severe atopic eczema to a standard course of narrowband ultraviolet B phototherapy by using validated objective and subjective scoring systems.

Full description

Children with moderate to severe atopic eczema prescribed a course of narrowband UVB phototherapy were scored (using validated scoring systems) objectively and subjectively before, during and after the course of treatment, as well as 3 and 6 months post treatment (to determine length of remission). Their scores were compared to a control group. The control group comprised children with moderate to severe atopic eczema who were offered UVB but were unable to undertake the treatment.

Enrollment

58 patients

Sex

All

Ages

3 to 16 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Children aged 3-16 years with moderate to severe atopic eczema (as defined by the modified Hannifin and Rajka criteria) in whom there is a clinical indication for phototherapy (as deemed by their specialist Dermatology consultant).

Exclusion criteria

  • Children under the age of 3 years or any child who lacks the maturity needed to stand in the phototherapy cabinet unsupervised.
  • Mild disease (defined as a Six Area Six Sign Atopic Dermatitis (SASSAD) score <10)

Trial design

58 participants in 2 patient groups

UVB
Description:
Children with moderate to severe atopic eczema who undertook a standard course of narrowband Ultraviolet B (NBUVB) phototherapy
Treatment:
Radiation: Narrowband Ultraviolet B phototherapy
Controls
Description:
Children with moderate to severe atopic eczema who were offered UVB but were unable to undertake treatment

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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