Nasal Fentanyl And Renal Colic

Valduce Hospital

Status: Completed

Conditions: Acute Renal Colic

Treatments: Drug: FENTANYL; Drug: Ketorolac Tromethamine AND morphine

Study type: Interventional

Funder types: Other

Identifiers

NCT01339624

NASAL FENTANYL-01

Details and patient eligibility

About

The purpose of this study is to determine whether nasal fentanyl is effective in the treatment of renal colic in adults in emergency department.

Enrollment: 65 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The patients were adults aged 18 to 65 years, presenting in ED with classical clinical symptoms of renal colic (sudden monolateral flank pain with inguinal irradiation) with a 10-cm visual analog scale (VAS) greater than or equal to 7

Exclusion criteria

• Were analgesia within 6 hours of arrival
• Allergy to opiates and NSAIDs
• Opiates abuse, known or suspected abdominal aortic dissection or aneurism,
• Presence of peritonitis
• Hemodynamic instability
• Pregnancy, breastfeeding, anticoagulant therapy.
• Patients with known renal, pulmonary, cardiac or hepatic failure, as well as those with renal transplantation, were also excluded.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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65 participants in 2 patient groups

NASAL FENTANYL,

Active Comparator group

Treatment:

Drug: FENTANYL

KETOROLAC + MORPHINE

Active Comparator group

Treatment:

Drug: Ketorolac Tromethamine AND morphine