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Nasal High Flow in Bariatric Surgery

I

Istanbul University

Status

Unknown

Conditions

Morbid Obesity

Treatments

Other: Oxygen therapy via face mask
Other: Oxygen therapy via HFNC

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

High frequency nasal cannula (HFNC) provides an inspiration O2 fraction of 21-1% and it has a minimal dead space and can be well tolerated due to humidified air. Group I patients will be applied HFNC before and after bariatric surgery, Group II patients will be applied a constant O2 concentration via face mask. Oxygen pressure, oxygen saturation, carbon dioxide, respiration frequency, forced vital capacity will be measured before and after surgery.

Full description

Morbid obese patients are prone to atelectasis and hypoxemia after bariatric surgery. High frequency nasal cannula (HFNC) provides an inspiration O2 fraction of 21-1% and it has a minimal dead space and can be well tolerated due to humidified air. It provides 5-7 cm H2O positive end expiratory pressure to the airways and may prevent atelectasis. In the preoperative room, forced vital capacity, peripheral oxygen saturation (SpO2), respiratory frequency, heart rate (HR), blood pressure (BP), carbon dioxide, oxygen pressure and carbon dioxide partial pressure values in blood gas analysis will be recorded. We will apply HFNC in the preoperative and postoperative period to Group I patients, while applying a constant O2 concentration to Group II patients. After appliying HFNC for two hours in Group I patients and O2 via face mask in Group II patients measurements will be repeated. During surgery, similar mechanical ventilation parameters will be applied to the patients. After the operation Group I patients will be applied HFNC, while Group II patients will be applied O2 via face mask in the recovery room for two hours. Measurements will be repeated. Primary end point of the study is the association between oxygen pressure, carbon dioxide partial pressure values among preoperative before and after HFNC and O2 and postoperative times.

Enrollment

112 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Patients with a body mass index of 40-55 kg/m2
  • American Society of Anesthesiologists score II-III
  • Patients undergoing laparoscopic sleeve gastrectomy or one anastomosis gastric bypass

Exclusion criteria

  • Obstructive sleep apnea syndrome
  • Using a non invasive mechanical ventilation device preoperatively
  • Patients whoo will predicted to postanesthesia care unit admission postoperatively

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

112 participants in 2 patient groups

Oxygen therapy via HFNC
Active Comparator group
Description:
Patients who will be applied high frequency nasal cannula before and after surgery
Treatment:
Other: Oxygen therapy via HFNC
Oxygen therapy via face mask
Active Comparator group
Description:
Patients who will be applied O2 via face mask before and after surgery
Treatment:
Other: Oxygen therapy via face mask

Trial contacts and locations

0

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Central trial contact

Guniz Koksal; Cigdem A BEYOGLU

Data sourced from clinicaltrials.gov

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