Nasal Ointment on Epistaxis of Nasotracheal Intubation in Children

Ajou University School of Medicine

Status: Completed

Conditions: Epistaxis; Intubation

Treatments: Drug: tarivid ointment

Study type: Interventional

Funder types: Other

Identifiers

NCT04426409

AJIRB-MED-INT-19-508

Details and patient eligibility

About

Nasotracheal intubation is one of the anesthetic procedures required for oral surgery. It allows the surgeon easier access to the surgical site than the orthotracheal intubation. Therefore, nosotracheal intubation is commonly used for general anesthesia for oral and maxillofacial surgery and dental treatment. However, nasotracheal intubation can damage the nasal mucosa in the course of the tube passing through the nostrils, causing epistaxis which is reported as the most common side effect.

In order to reduce these side effects, heating of the tube and use of a tube lubricant immediately before intubation have been recommended in children. However, research on whether the dry state of the mucosa itself contributes to the development of epistaxis is limited. A study in adults reported that pretreatment of the ointment on the mucosa reduced the damage to the mucosa. However, its effect on the incidence of epistaxis in children has not been studied.

The purpose of this study is to investigate the effects of pretreatment of nasal ointment on epistaxis of nasotracheal intubation in children.

Enrollment: 108 patients

Sex: All

Ages: 4 to 8 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists physical statue I or II
• Patients scheduled to undergo surgery under nasotracheal intubation

Exclusion criteria

• expected difficult intubation based on history, physical examination, weight.
• bleeding tendency
• upper respiratory infection within the previous 14 days

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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108 participants in 2 patient groups

control group

No Intervention group

ointment group

Experimental group

Description:

Ointment group should apply a nasal ointment to both noses using a cotton swab the night before surgery and the morning of surgery.

Treatment:

Drug: tarivid ointment