Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep

University of Pennsylvania

Status: Enrolling

Conditions: Sleep Apnea, Obstructive

Study type: Observational

Funder types: Other

Identifiers

NCT06789770

857046

Details and patient eligibility

About

This project will provide important new information regarding (1) the relationship between route of breathing and airway collapsibility and (2) whether route of breathing during DISE (Drug-Induced Sleep Endoscopy) is representative of natural sleep.

Full description

As part of standard of care, a drug-induced sleep endoscopy will be done, where route of breathing will be determined as a percentage of total breaths (during baseline, lateral sleep and maneuver). As part of the research procedure, an in-laboratory Polysomnogram will be conducted as study procedure including a oronasal pressure signal cannula to assess route of breathing.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• • Adults (≥ 18yrs) that underwent clinical evaluation at the CPAP Alternatives Clinic at Penn Otorhinolaryngology.

  • Must have at least mild OSA (AHI>5)

Exclusion criteria

• • Sleep study with an AHI<5, >25% of total events being central or mixed events, or inability to achieve adequate drug-induced sleep.

  • Upper Respiratory Illness at the time of the DISE.