NASH in Subjects With Different Classes of Obesity (CONNECT)

Catholic University of the Sacred Heart

Status: Unknown

Conditions: Obesity; NAFLD; NASH - Nonalcoholic Steatohepatitis; Obesity, Morbid

Treatments: Procedure: Liver biopsy

Study type: Observational

Funder types: Other

Identifiers

NCT04653103

20202011

Details and patient eligibility

About

It is an observational trial on 500 subjects. The purpose of this trial is to assess the prevalence of non-alcoholic steatohepatitis (NASH) in subjects with different classes of obesity.

Full description

Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most common cause of chronic liver disease due to an increase in the prevalence of obesity. The development of NASH leads to an increase in morbidity and mortality. Since patients with obesity are at an increased risk of NASH, the aim of this trial is to assess the prevalence of NASH in this class of patients.

Enrollment: 500 patients

Sex: All

Ages: 19 to 69 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged between 19 and 69 years

Exclusion criteria

• Pregnancy
• Active cancer
• End stage renal failure
• End stage liver failure
• Being unable to understand and sign informed consent

Trial design

500 participants in 1 patient group

Patients with obesity

Description:

Subjects with different classes of obesity

Treatment:

Procedure: Liver biopsy