Nasogastric Tube in Premature Babies - Pain and Treatment

Norwegian University of Science and Technology

Status and phase: Completed; Phase 2

Conditions: Infant, Premature

Treatments: Other: sterile water; Device: Pacifier; Drug: Sucrose

Study type: Interventional

Funder types: Other

Identifiers

NCT00218946

NISE-2005-1

Details and patient eligibility

About

Does sucrose or pacifier influence pain in premature babies when a nasogastric tube is inserted?

Full description

A total of 24 premature babies are randomised to receive either placebo (sterile water), 30 % sucrose, or pacifier in a complete factorial, cross-over design. Pain is rated on the PIPP scale by observers blinded to the procedure other than use of pacifier.

Enrollment: 24 patients

Sex: All

Ages: 3 days to 8 weeks old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 28 - 32 weeks gestational weeks
• not on mechanical ventilation

Exclusion criteria

• high risk group regarding cerebral prognosis

Trial design

24 participants in 6 patient groups

control

No Intervention group

Description:

no fluid, no pacifier

water

Experimental group

Description:

water, no pacifier

Treatment:

Other: sterile water

sucrose

Experimental group

Description:

Sucrose, no pacifier

Treatment:

Drug: Sucrose

pacifier

Experimental group

Description:

No fluid, pacifier

Treatment:

Device: Pacifier

water and pacifier

Experimental group

Description:

water, pacifier

Treatment:

Device: Pacifier

sucrose and pacifier

Experimental group

Description:

sucrose, pacifier

Treatment:

Drug: Sucrose

Device: Pacifier