Nasogastric Tube vs. Orogastric Feeding Tube in Preterm Infants: Which is Best?

Hillel Yaffe Medical Center

Status

Completed

Conditions

Infant, Premature

Treatments

Procedure: Feeding tube insertion

Study type

Interventional

Funder types

Other

Identifiers

NCT00365703

17/2006-1-HY-CTIL

Details and patient eligibility

About

The purpose of this study is to find out which method (nasogastric vs. orogastric) of feeding tube for premature infants results in earlier only oral feeding.

Full description

Preterm infants, even as young as 23 weeks gestational age, can be fed enterally at the first week of life. Coordination of sucking and swallowing, and coordination of both and breathing is necessary for efficient and safe oral feeding, and is not well established before the 35th week gestational age. That is why tube feeding is essential for preterm infants younger than that age.

There is no consensus regarding the best way for the feeding tube, i.e. oral vs. nasal, and whether placing the tube should be continuous or intermittently. Nasogastric tube has been associated with vagal responses. Both tubes may cause gastric perforation.

Development and function of oral feeding has been described. It is known that non-nutritive sucking and early introduction of oral feeding accelerate the transition from tube feeding to oral feeding. It is suggested that the preterm infant may experience a maturational lag in vagal function related to ingestive needs, which may contribute to continued feeding difficulties and may be a measurable marker of subtle neurodevelopmental problems. Both oral and nasal feeding tube may interfere with establishment of efficient oral feeding. The purpose of this study is to see whether there is a difference between oral and nasal tube feeding, regarding the institution of oral feeding.

Enrollment

115 patients

Sex

All

Ages

Under 4 months old

Volunteers

No Healthy Volunteers

Inclusion criteria

All preterm infants, born during one year, who required tube feeding, and later discharged from neonatal intensive care unit.

Exclusion criteria

Infants who died during hospitalization
Infants with severe neurologic deficit (e.g. after Sarnat II-III asphyxia, or as a part of a syndrome
Infants with gastrostomy
Infants who were transferred to another hospital for any reason (e.g. heart surgery)