Nasopharyngeal 24 Hour pH Monitoring in Health Adult Volunteers

University of California (UC) Davis

Status: Withdrawn

Conditions: Gastroesophageal Reflux Disease

Treatments: Device: Dx-pH Measurement Probe

Study type: Interventional

Funder types: Other

Identifiers

NCT00584675

200714988-1

Details and patient eligibility

About

Involves a 24-hour pH probe study using the Dx-pH Measurement System on patients who do not have symptoms of laryngopharyngeal reflux or gastroesophageal reflux disease to establish normal values for the Dx-pH Measurement System.

Full description

The specific aim of this study is to establish the normal range of values in an adult population with no symptoms of laryngopharyngeal reflux disease or gastroesophageal reflux disease using the Dx-pH Measurement System.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 years of age or older
• no symptoms of laryngopharyngeal reflux or gastroesophageal reflux disease
• score less than 10 on Reflux Symptom Index

Exclusion criteria

• age less than 18
• known lidocaine allergy
• history of heartburn, regurgitation, chronic cough, voice changes, globus pharyngeus, excessive throat clearing, or swallowing problems
• score 10 or greater on Reflux Symptom Index
• current or past antacid use or other antireflux therapy
• history of antireflux surgery
• pregnancy
• current anticoagulation therapy (warfarin, heparin, aspirin, clopidogrel bisulfate)
• special/vulnerable populations (children, mentally handicapped, pregnant women, fetuses, prisoners, cognitive impairment, life-threatening disease, social or economic disadvantage)