National Evaluation of PI-based 2nd Line Efficacy in Cambodia

ANRS, Emerging Infectious Diseases

Status: Completed

Conditions: HIV

Study type: Observational

Funder types: Other

Identifiers

NCT01801618

ANRS12276 2PICAM

Details and patient eligibility

About

Medium and long term efficacy of PI-based 2nd line antiretroviral (ARV) therapy in Cambodia is poorly documented when the numbers of patients on treatment and their duration are increasing. For patients in treatment failure , there is no alternative ARV regimen available to date.

This operational research aims to evaluate the Cambodian National Program PI-based 2nd line antiretroviral regimen to assess the proportion of treatment failure and drug resistance ;identify the structural and individual factors associated with treatment failure ; design alternative salvage ARV regimens.

Enrollment: 15,001,351 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HIV infection
• age above 18 years
• current PI based 2nd line ARV treatment since at least 6 months
• willing to participate and consent signature

Exclusion criteria

• ongoing PI based 2nd line regimen for less that 6 months at time of study intake