Nationwide Treatment Survey of Intracranial Arteriovenous Malformation in China (NTSIAVMC)

Dr. Yong Cao

Status: Unknown

Conditions: Intracranial Arteriovenous Malformations

Study type: Observational

Funder types: Other

Identifiers

NCT01803685

IAVM-125R

Details and patient eligibility

About

This register study will collect the treatment information of the intracranial arteriovenous malformation patients in China. We aim to understand the current treatment situation of the disease in China.

Full description

Intracranial arteriovenous malformations are congenital lesions that consist of multiple arteries and veins, connecting as a fistula without intervening normal capillary bed. The treatment strategy including surgical removal, endovascular embolism and stereotaxic radiosurgery and comprehensive treatment. China is a united multi-ethnic nation of 56 ethnic groups, and has the largest population in the world. We have most extensive and valuable clinical resources of intracranial arteriovenous malformation in the world. But we know little about the current treatment situation of the disease in China.

In order to realize the treatment situation of intracranial arteriovenous malformation in China, we designed a retrospective and prospective register study to collect the treatment and outcome information all over China.

Enrollment: 1,000 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• All the patients that diagnosed of intracranial AVM by DSA/CT/MRI
• All patients gave written informed consent

Exclusion criteria

• patients refuse to attend the survey

Trial design

1,000 participants in 5 patient groups

Surgical treatment

Description:

Surgical resection of intracranial arteriovenous malformations.

Stereotaxic radiosurgery

Description:

Deliver a relatively high dose of focused radiation precisely to the arteriovenous malformations.

Endovascular treatment

Description:

Deliver embolic materials to the feeding arteries or the nidus by microcatheters

Comprehensive treatment

Description:

Use two or three methods ( Surgical treatment stereotaxic radiosurgery endovascular treatment ) to cure the intracranial arteriovenous malformations

Conservative treatment

Description:

Patients refused to any of the treatment above