Natriuretic Peptides After Left Atrial Appendage Amputation

University of Giessen

Status: Completed

Conditions: Atrial Fibrillation

Treatments: Procedure: LAA amputation

Study type: Interventional

Funder types: Other

Identifiers

NCT03816410

SR-345-DP

Details and patient eligibility

About

Surgical amputation of the left atrial appendage (LAA) is an established intervention during surgical atrial fibrillation (AF) therapy. However, its effects on the endocrine function of the left atrium are unclear. This study aims to quantify the serum levels of natriuretic peptides in patients who undergo concomitant surgical AF ablation with or without LAA amputation.

Enrollment: 21 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Indication for concomitant AF therapy during cardiac surgery with cardiopulmonary bypass

Exclusion criteria

• Lack of informed consent

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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21 participants in 2 patient groups

LAA amputation group

Experimental group

Treatment:

Procedure: LAA amputation

No LAA amputation group

No Intervention group