Natural Cycle Versus Endometrial Preparation for Healthy Blastocyst Transfer

European Hospital

Status: Completed

Conditions: Infertility

Treatments: Other: embryo transfer

Study type: Interventional

Funder types: Other

Identifiers

NCT02378584

CC1978MA

Details and patient eligibility

About

This study evaluates the difference in pregnancy rate transferring a healthy blastocyst in natural or artificial cycle.

Full description

The aim of the study was to verify the implantation capacity and ongoing pregnancy rate of vitrified warmed euploid blastocyst in natural cycle versus endometrial artificial cycle with gonadotropin-releasing hormone (GnRH-agonist) pituitary suppression.

Enrollment: 236 patients

Sex: Female

Ages: 20 to 42 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• frozen-thawed healthy blastocyst

Exclusion criteria

• post thawed not survival healthy blastocyst

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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236 participants in 2 patient groups

natural cycle

Other group

Description:

Ultrasound controls and endocrine blood test to asses the day of ovulation for embryo transfer

Treatment:

Other: embryo transfer

hormonal cycle

Active Comparator group

Description:

Ultrasound controls and endocrine blood test to asses the endometrium thickness for embryo transfer

Treatment:

Other: embryo transfer