Natural History of Carotid Atherosclerosis

National and Kapodistrian University of Athens

Status: Unknown

Conditions: Carotid Artery Disease; Stroke; Angina Pectoris; Myocardial Infarction

Study type: Observational

Funder types: Other

Identifiers

NCT01521351

MRcar

Details and patient eligibility

About

A prospective study of 700 patients with coronary artery disease will undergo non invasive evaluation of their carotid arteries by ultrasound and microwave radiometry. The patients will be followed up for 3 years and their outcome regarding the cardiovascular events (death, cardiac events, cerebrovascular events) will be recorded

Full description

Carotid artery Thermal heterogeneity recorded by MR will be corelated to cardiovascular events (death, cardiac events, cerebrovascular events) as well as to all demographic (age, sex, hypertension, dyslipidemia, smoking status, etc) factors

Enrollment: 700 estimated patients

Sex: All

Ages: 30 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consecutive patients with coronary artery disease admitted in our hospital

Exclusion criteria

• Patients with history of previous cerebrovascular event,
• History of vasculitis, intermittent inflammatory, infectious, or neoplastic conditions likely to be associated with an acute-phase response.

Trial design

700 participants in 4 patient groups

carotid thermal heterogeneity

Description:

Patients that have carotid thermal heterogeneity detected by MR

no carotid thermal heterogeneity

Description:

Patients that DONT have carotid thermal heterogeneity detected by MR

carotid artery disease

Description:

Patients with detected carotid artery disease by ultrasound

no carotid artery disease

Description:

Patients with no carotid artery disease detected by ultrasound