Natural History of Eosinophilic Esophagitis (EoE)

Mayo Clinic

Status: Completed

Conditions: Eosinophilic Esophagitis

Treatments: Diagnostic Test: Physical Examination and Questionnaires; Diagnostic Test: Barium Esophagram; Device: EsophaCap

Study type: Observational

Funder types: Other

Identifiers

NCT03290482

17-002067

Details and patient eligibility

About

Researchers are trying to understand the course of Eosinophilic Esophagitis (EoE), its progression and effects of treatments.

Full description

Investigators will identify patients from their database who have been diagnosed with Eosinophilic Esophagitis (EE) from the study period 2000 to 2008, based on clinical features and biopsy findings. Participants will be offered a follow up evaluation that includes: evaluation by the Principal Investigator, completion of questionnaires, Esophagram and Esophageal sponge (EsophaCap) cytology.

Enrollment: 65 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults 18 years of age and older
• Previous participation in the natural history followup study

Exclusion criteria

• Inability to read due to: Blindness, cognitive dysfunction, or English language illiteracy
• Pregnant women

Trial design

65 participants in 1 patient group

EE Study Patients 2000-2008

Description:

All patients with the diagnosis of EE from the study period 2000 to 2008. Sixty patients participated in the 10 year follow up phone interview and questionnaire. These are the subjects we will contact to see if they are interested in participating in this study. If interested in participating, subjects will complete: 1. Evaluation by the PI physical examination 2. Complete the modified Mayo dysphagia Questionnaire (MDQ) and the Eosinophilic Esophagitis Activity Index (EEsAI) questionnaires 3. Barium Esophagram with maximal and minimal esophageal diameter measurement 4. EsophaCap cytology

Treatment:

Device: EsophaCap

Diagnostic Test: Physical Examination and Questionnaires

Diagnostic Test: Barium Esophagram