Natural History Study of Azathioprine Adherence

Thomas E. Nivens, MD

Status: Completed

Conditions: Kidney Transplant

Treatments: Other: observation

Study type: Observational

Identifiers

NCT00143910

9109M04306

NIH - DK13083

Details and patient eligibility

About

This study began in 1993 as a prospective, natural history study of renal transplant patients' medication compliance measured by using an electronic monitor on the cap of medication vials. Hypothesis: Poor medication compliance predicts adverse outcomes. Enrollment is closed.

Full description

• The study is complete. Patient recruitment is closed and active patient involvement in the study has ended.
• Statistical analysis of monitor records and new patient outcome data continues

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Kidney transplant recipient
• Discharged from hospital with functioning graft,not on dialysis
• Prescribed azathioprine

Exclusion criteria

• Unable to give informed consent
• Non English speaking
• Previous or concurrent organ transplant other than kidney
• Taking liquid form of azathioprine
• Followed outside of the United states

Trial design

180 participants in 1 patient group

Renal transplant recipient

Description:

Recipients of successful renal transplant

Treatment:

Other: observation