Navigation and Free Recall in Chronically Implanted Humans

Barbara Jobst

Status: Completed

Conditions: Epilepsy

Treatments: Other: electrical stimulation

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT02781129

D16119

Details and patient eligibility

About

This study is designed to identify brain activity associated with good memory in subjects with a chronically implanted RNS® device and to study the effects of therapeutic stimulation for epilepsy on memory. This will be accomplished through analysis of ECoG data collected during memory encoding for short and long-term free recall as well as during navigation tasks.

Enrollment: 9 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• able to give informed consent
• 18 years of age or older
• Diagnosis of epilepsy
• Implanted RNS® device and receiving therapeutic stimulation for epilepsy.
• Capable of completing experimental tasks in the judgment of the Principal Investigator

Exclusion criteria

• RNS® Neurostimulator implanted within 3 months of experimental tasks.

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

9 participants in 1 patient group

RNS® Neurostimulator

Experimental group

Description:

Subjects with pharmaceutically intractable seizures who have been implanted with a RNS® Neurostimulator.

Treatment:

Other: electrical stimulation