Nebulized Lidocaine to Prevent Cough at Emergence From Anesthesia

Mongi Slim Hospital

Status: Unknown

Conditions: Cough, General Anesthesia, Extubation, Lidocaine, Sore Throat

Treatments: Drug: Lidocaine 2%; Drug: Normal saline

Study type: Interventional

Funder types: Other

Identifiers

NCT04000633

lidocaïne cough prevention

Details and patient eligibility

About

our study aimed to evaluate the effect of nebulized lidocaine to decrease the incidence of cough and sore throat after extubation after surgeries requiring endotracheal intubation.

Full description

our study aimed to evaluate the effect of nebulized lidocaine to decrease the incidence of cough and sore throat after extubation after surgeries requiring endotracheal intubation.

This randomized controlled study will compare the effect of Lidocaine and placebo nebulization in the immediate pre operative period in order to evaluate the effectiveness in reducing post extubation cough and sore throat.

Enrollment: 80 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age>18 years
• ASA status I or II

Exclusion criteria

• Unexpected difficult laryngoscopy
• Surgery>3 hours

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 2 patient groups, including a placebo group

lidocaine group

Active Comparator group

Description:

the patients of this group will recieve nebulization of 5 ml of 2% lidocaine prior to induction of general anesthesia

Treatment:

Drug: Lidocaine 2%

Placebo group

Placebo Comparator group

Description:

the patients of this group will recieve nebulization of 5 ml of normal saline prior to induction of general anesthesia

Treatment:

Drug: Normal saline