Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma

Hamad Medical Corporation (HMC)

Status: Unknown

Conditions: Asthma

Treatments: Drug: Magnesium Sulfate

Study type: Interventional

Funder types: Industry

Identifiers

NCT01584726

#12095/12

Details and patient eligibility

About

The purpose of this study is to investigate the use of magnesium sulfate nebulization in patient with moderate to severe asthma exacerbation in pediatric emergency.

Full description

the use of magnesium sulfate nebulization in patient with moderate to severe asthma exacerbation in pediatric emergency

follow asthma severity score and length of stay

Enrollment: 400 estimated patients

Sex: All

Ages: 2 to 14 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pediatric asthma patients with moderate to severe exacerbation

Exclusion criteria

• Known allergy to magnesium sulfate
• History of neuromuscular disease, cardiac disease, renal disease, or underlying chronic lung disease
• Use of oral steroid medication within 72 hours of presentation
• Radiographic evidence of pneumonia at presentation
• Administration of intravenous magnesium sulfate prior to study enrollment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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400 participants in 2 patient groups

magnesium sulfate arm

Other group

Description:

magnesium sulfate with standard therapy

Treatment:

Drug: Magnesium Sulfate

placebo arm

No Intervention group

Description:

placebo with standard therapy