Negative Predictive Value of Drug Provocation Tests to Beta-lactams (NPVDPT)

University Hospital Center (CHU)

Status: Terminated

Conditions: Drug Hypersensitivity

Treatments: Other: Evaluation of reexposure to a negatively tested betalactam

Study type: Interventional

Funder types: Other

Identifiers

NCT02844712

9394

Details and patient eligibility

About

Patients with a complete drug allergy work-up to betalactam antibiotics were contacted (by mail) and asked to answer a questionnaire regarding the tolerance upon readministration of a negatively tested beta-lactam.

Enrollment: 750 patients

Sex: All

Ages: 5+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elderly patients with at least 5 years at the time of consultation for allergy suspected allergy to beta-lactam antibiotics in the University Hospital of Montpellier and with a negative provocation test to a betalactam
• The patient or the patient's legal representatives are not their opposition to participate in this study
• The patient must be affiliated or beneficiary in a health insurance system

Exclusion criteria

• The patient is exclusion period determined by a previous study
• The patient is under judicial protection, guardianship or curatorship
• The patient or the patient's legal representatives do not read fluently the French language

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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750 participants in 1 patient group

Evaluation of reexposure to a negatively tested betalactam

Other group

Treatment:

Other: Evaluation of reexposure to a negatively tested betalactam