Negative Pressure Ventilation Imapcts Weaning Ventilator In Medical Intensive Care Units (ICUs)

Chang Gung Medical Foundation

Status and phase: Unknown; Phase 2

Conditions: Respiratory Failure

Treatments: Behavioral: negative pressure ventilator use

Study type: Interventional

Funder types: Other

Identifiers

NCT01155596

98-3276B

Details and patient eligibility

About

This is a Quasi-experimental research design. The subjects are limited in intensive care unit within north medical center hospital. All subjects depend on ventilator and receive weaning plans. Experimental group is weaning with the support of negative pressure ventilator .The investigators collect basic personal variables in the questionnaire, APACHE Ⅱ scale, Dyspnea scale and arterial blood gas analysis and ventilator weaning index. Compare experimental group and control group data. Data will be Statistical analyzed by: descriptive statistics (such as: mean, standard deviation, median, frequency, percentage) and inferential statistics (such as: Independent T-test, Pair T-test, Mann-Whitney U test), P-value <0.05 will consider to be statistically significant.

Enrollment: 120 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acute respiratory failure patients in medical ICUs

Exclusion criteria

• Age<20 years old
• Malignancy
• Pregnancy

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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120 participants in 2 patient groups

Control group

No Intervention group

Description:

Base on positive pressure ventilation with intubation and mechanical ventilator, weaning processes will undergo by Pulmonologists.

Experimental group

Experimental group

Description:

Experimental group is weaning with the support of negative pressure ventilator.

Treatment:

Behavioral: negative pressure ventilator use