Neighborhoods, Networks, Depression, and HIV Risk (Workshop)

Johns Hopkins Bloomberg School of Public Health

Status and phase: Completed; Phase 2

Conditions: HIV; Depression; Drug Use

Treatments: Behavioral: Workshop; Behavioral: Workshop control

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT01380613

DESPR-DA022961-03

R01DA022961 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The goal of this study is to examine how social networks, neighborhood, and depression are related to HIV risk. The intervention is designed to train individuals to cope with feelings of depression or stress as a way to reduce their risk for HIV.

Full description

This study included implementation and evaluation of a small group, randomized controlled, phase II intervention to reduce depressive symptoms and HIV risk behaviors among inner city drug users. The intervention included elements of cognitive behavioral therapy (CBT) for depression among impoverished individuals, emphasizing depressive cognitions and behaviors theorized to be associated with depression and with HIV risk behaviors among mildly to moderately depressed drug users. In addition, the study examined active drug users' social and environmental pathways to depression and subsequent HIV risk behaviors. Specifically, we will hypothesized mediating/moderating effects of neighborhood characteristics, social network factors, and individual level factors on depressive symptoms and HIV risk behaviors.

Enrollment: 965 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. 18-55 years old
2. HIV Risk Behavior:

3a. Injected drugs more than 3 times in the past week OR

3b. Snorted/sniffed heroin or cocaine or smoked crack in the past 6 months AND had 1 of the following sex risks in the past 6 months: i) 2 or more sex partners ii) Had a sex partner who injected drugs iii)Had a sex partner who smoked crack iv) Had a sex partner who was HIV+

4. Willingness to attend group sessions

Exclusion criteria

1. Enrolled in another HIV behavioral intervention or depression study in past the 3 years
2. Enrolled in another Lighthouse study in past the 5 years
3. Enrolled in the formative research (Phase 1) or pilot (Phase 2) of the current project.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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965 participants in 2 patient groups

Workshop Control

Active Comparator group

Description:

Participants receive HIV/STDs risk reduction information.

Treatment:

Behavioral: Workshop control

Intervention Workshop

Experimental group

Description:

Participants learn skills to cope with depressive symptoms and stress as well as safer sex and injection skills.

Treatment:

Behavioral: Workshop