Neoadjuvant Chemotherapy in Non Small Cell Lung Cancer (NSCLC) Stages IB, IIA, IIB, and IIIA/T3

Rigshospitalet

Status and phase: Terminated; Phase 3

Conditions: Non-small Cell Lung Cancer

Treatments: Drug: Carboplatin and Paclitaxel

Study type: Interventional

Funder types: Other

Identifiers

NCT00273507

Neoadjuvant treatment in NSCLC

Details and patient eligibility

About

Randomised trial of chemotherapy or not before surgery in early resectable stages of NSCLC (IB, IIA, IIB, and IIIA/N2).

Full description

Randomisation between 3 courses of neoadjuvant Carboplatin plus Paclitaxel or no chemotherapy before surgery.

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• NSCLC
• Stages IB, IIA, IIB, IIIA/T3
• Lung function test allowing surgery
• Age 18-75 years

Exclusion criteria

• Poor lung function
• Performance status 3-4
• Mediastinal lymph node involvement

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)