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Neoadjuvant Chemotherapy Response in Metaplastic Carcinoma of Triple Negative Breast Cancer (NEO-SMART)

Seoul National University logo

Seoul National University

Status

Terminated

Conditions

Metaplastic Breast Carcinoma

Treatments

Diagnostic Test: Vimentin/pan CK stain

Study type

Observational

Funder types

Other

Identifiers

NCT04549584
2004-261-112

Details and patient eligibility

About

prospective study for response of neoadjuvant chemotherapy in metaplastic carcinoma of triple negative breast cancer

Full description

Vimentin/Pan CK staining will be performed on tissues of patient who visited Seoul National University Hospital and were diagnosed with triple negative breast cancer and decided to perform neoadjuvant chemotherapy under clinical judgement.

Histologically determined to be a metaplastic breast cancer or tested positive for vimentin/Pan CK patients decides as the metaplastic breast cancer. They evaluate the response rate of the neoadjuvant chemotherapy.

Patients with vimentin/Pan CK negative are diagnosed with non-metaplastic breast cancer and this group also confirms the response rate of neoadjuvant chemotherapy.

The group of metaplastic breast cancer will enroll 50 people, and the group of non-metaplastic breast cancer will enroll 100 people.

Enrollment

3 patients

Sex

All

Ages

20+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • over 20 years old
  • patients with triple negative breast cancer diagnosed Seoul National University Hospital
  • patients who decided to perform neoadjuvant chemotherapy under clinical judgement

Exclusion criteria

  • not applicable

Trial design

3 participants in 2 patient groups

metaplastic breast cancer
Description:
Histologically determined to be a metaplastic breast cancer or tested positive for vimentin/Pan CK patients decides as the metaplastic breast cancer.
Treatment:
Diagnostic Test: Vimentin/pan CK stain
non-metaplastic breast cancer
Description:
Patients with vimentin/Pan CK negative are diagnosed with non-metaplastic breast cancer

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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