Neopterin Dosage in the Eye (CHA)

Intermunicipal Hospital Center Toulon

Status

Completed

Conditions

Cataract

Treatments

Biological: Samples

Study type

Observational

Funder types

Other

Identifiers

NCT03497481

2017-CHITS-02

2017-A00183-47 (Other Identifier)

Details and patient eligibility

About

The purpose of the study is to determine whether neopterin can be dosed in the fluid of the eye's anterior chamber for patient with non-inflammatory and non-infectious ophthalmic pathology.

Full description

The study will be explained to subjects who are about to undergo ophthalmologic surgery. They will sign an informed consent and be included in the study. Urine sample will be collected specifically for the study. Eye's anterior chamber fluid will also be collected during the surgery as it is the usual practice (the sample is used for the neopterin dosage instead of being thrown away).

These samples will be centrifuged, frozen in a -80° C freezer. At the end of the study, all the samples will be sent to the central Lab for the neopterin dosage analysis. Results will be communicated to the principal investigator afterward.

Enrollment

20 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age ≥ 18 years-old
Non inflammatory or non infectious ophthalmic pathology requiring puncture of eye's anterior chamber fluid.
Minimum of 200 microliter sample
Immunocompetent subjects
Signed and dated informed consent
Samples management in accordance with the pre-analytical conditions specified in the protocol

Non-inclusion criteria:

Age < 18 years-old
Subjects treated with intraocular corticoids, antibiotics or anti-inflammatory, locally or in systemic injection, prior to inclusion.

Exclusion criteria