Nervous System Symptoms Associated With COVID 19 (NS-COV)

Toulouse University Hospital

Status: Completed

Conditions: Covid19

Treatments: Other: NEURO +; Other: NEURO -

Study type: Interventional

Funder types: Other

Identifiers

NCT04922905

RC31/20/0178

Details and patient eligibility

About

This study aim to prospectively evaluate the neuropsychiatric symptoms of patients infected with the SARS-CoV-2 virus by a standardized neuropsychiatric examination : the global CASE scale (Clinical Assessment Scale in Autoimmune Encephalitis), and the prevalence of disturbances of consciousness, focal neurological deficit, cognitive impairment, headache, anosmia, sleep disturbances, impaired autonomic nervous system and peritraumatic stress.

Enrollment: 99 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Being hospitalized at the Toulouse University Hospital for a COVID-19 infection proven by a probable PCR or COVID-type examination on the chest scan
• Have given oral consent for the collection of clinical neurological data
• Be in a clinical state compatible with a 30-minute neurological examination
• Be French-speaking
• Be affiliated to a Social Security scheme

Exclusion criteria

• Refusal of the neurological examination
• History of neurological pathology at a severe stage
• Pregnant or breastfeeding woman
• Persons with tutors or curators

Trial design

Primary purpose: Health Services Research

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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99 participants in 2 patient groups

NEURO +

Other group

Description:

Patients "neuro +" are those with a CASE score ≥ 2, "Neuro +" patients will benefit from additional evaluations using paraclinical examinations

Treatment:

Other: NEURO +

NEURO -

Other group

Description:

Patients "neuro -" are those with a CASE score \< 2

Treatment:

Other: NEURO -