Nesfatin-1 Level in Patients With Type 2 Diabetes, Insulin Resistance and Obesity

Istanbul Medeniyet University

Status: Unknown

Conditions: Insulin Resistance; Obesity; Nesfatin-1; Type 2 Diabetes

Treatments: Diagnostic Test: Nesfatin-1

Study type: Interventional

Funder types: Other

Identifiers

NCT04298515

HNEAH-KAEK 2019/100

Details and patient eligibility

About

This research was planned to determine the level of nesfatin-1, known as satiety hormone, in type 2 diabetes, insulin diabetes and obesity patients and to determine whether there is a relationship between patients' energy intake levels. Additionally, it was aimed to evaluate the relationship between patients' nesfatin-1 values and serum glucose, insulin, lipid concentrations.

Full description

Nesfatin-1 levels of patients with type 2 diabetes, insulin resistance and obesity will be measured. In addition, patients' daily food consumption will be taken and the amount of energy they receive will be calculated daily. The relationship between the level of nesfatin-1 in the blood and the energy received will be examined.

Enrollment: 180 estimated patients

Sex: All

Ages: 19 to 79 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Type 2 diabetes
• Insulin resistance
• Obesity disease

Exclusion criteria

• Pediatric individuals
• All patients who are hospitalized,
• Liver disease
• Cancer patients
• Disease related to the gastrointestinal tract
• Nephrological disease such as chronic kidney failure, acute kidney failure, nephrotic syndrome
• Neurological disease

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

---

180 participants in 3 patient groups

Type 2 Diabetes group

Other group

Description:

In case of fasting, blood will be taken from patients for the measurement of nesfatin-1.

Treatment:

Diagnostic Test: Nesfatin-1

Insulin resistance group

Other group

Description:

In case of fasting, blood will be taken from patients for the measurement of nesfatin-1.

Treatment:

Diagnostic Test: Nesfatin-1

Obesity group

Other group

Description:

In case of fasting, blood will be taken from patients for the measurement of nesfatin-1.

Treatment:

Diagnostic Test: Nesfatin-1