Network Effects of Therapeutic Deep Brain Stimulation

The University of Texas System (UT)

Status: Enrolling

Conditions: Intractable Epilepsy

Treatments: Device: RNS/DBS activation

Study type: Interventional

Funder types: Other

Identifiers

NCT05600738

HSC-MS-22-0045

Details and patient eligibility

About

The purpose of this study is to map the acute, short-term cortical evoked responses to thalamic electrical stimulation in persons with intractable epilepsy

Enrollment: 25 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis of Epilepsy
• undergoing neuromodulation therapy with clinically implanted neuromodulation devices (DBS, RNS)
• followed in the outpatient epilepsy clinic

Exclusion criteria

• pregnant women
• active psychosis, major depression, or suicidal ideation in the preceding year
• Intelligence quotient (IQ) less than 70 as measured by clinical neuropsychological evaluation
• Do not agree to share their medical records for research purposes

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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25 participants in 1 patient group

Treatment

Experimental group

Treatment:

Device: RNS/DBS activation