Neural and Cognitive Mechanisms of Depression and Anxiety: a Multimodal MRI Study

University of Electronic Science and Technology of China

Status: Unknown

Conditions: Depression

Study type: Observational

Funder types: Other

Identifiers

NCT02888509

UESTC-chenhuafulab-002

Details and patient eligibility

About

To explore the neural and cognitive mechanisms of depression (including unipolar depression and Bipolar disorder) and anxiety using multimodal MRI techniques.

Enrollment: 150 estimated patients

Sex: All

Ages: 16 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age range from 16 to 55 years old.
• All patients were interviewed by two experienced psychiatrists using the Structured Clinical Interview for DSM-IV (patient edition)

Exclusion criteria

• Schizophrenia, mental retardation or personality disorder, any history of loss of consciousness, substance abuse, serious medical or neurological illness.
• Subjects with contraindications to MRI

Trial design

150 participants in 4 patient groups

healthy control

Description:

Well mathed with patients in age, gender, education

major depression disorder

Description:

patients with major depression disorder

anxiety disorder

Description:

patients with anxiety disorder

bipolar depression disorder

Description:

patients with bilopar depression disorder