Neural Bases of Phantom Pain After Amputation (Phantom limb)

Direction Centrale du Service de Santé des Armées

Status

Not yet enrolling

Conditions

Phantom Pain

Treatments

Other: Proprioceptive training

Device: Brain and Spinal Cord functional Magnetic Resonance Imaging

Other: Questionnaires

Study type

Observational

Funder types

Other

Identifiers

NCT05545358

2020PPRC09

2021-A01733-38 (Other Identifier)

Details and patient eligibility

About

The amputation of a limb results in chronic pain associated with the lost limb in the majority of patients, which persists over time. Despite a large number of studies conducted in an attempt to elucidate the neural basis of phantom pain, these are still not elucidated and current treatments often fail to relieve patients' pain.

Enrollment

75 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Between 18 and 65 years old
For the "amputees with phantom pain" group: patients who have been amputated for more than 2 years and have chronic phantom pain
For the "amputees without phantom pain" group: patients who have been amputated for more than 2 years and do not have chronic phantom pain
For the "healthy participants" group: healthy participants with no neurological history

Exclusion criteria

Clinically significant pathology (gastrointestinal, renal, hepatic, endocrine, cardiovascular or respiratory)
Progressive psychiatric or neurological pathology
On psychotropic medication
Pregnant or nursing woman
Inadequate level of French language