Neural Bases of Post-stroke Emotion Perception Disorders (STROKEM)

University Hospital, Lille

Status

Enrolling

Conditions

Stroke

Stroke Sequelae

Emotions

Study type

Observational

Funder types

Other

Identifiers

NCT05595005

2020-A00193-36 (Other Identifier)

2019_12

Details and patient eligibility

About

This monocentric physiological study will evaluate the neural bases of visual recognition of emotions in stroke patients vs. healthy controls using MRI (functional and structural connectivity) and EEG.

Full description

This monocentric physiological study will evaluate the neural bases of visual recognition of emotions in stroke patients vs healthy controls (2 groups of 40 subjects). It will include functional MRI, structural MRI (disconnectome), EEG, and behavioral assessments of emotion recognition and executive functions.

Enrollment

80 estimated patients

Sex

All

Ages

18 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Stroke group:

Man or Woman
Age 18-80y
Unique stroke, ischemic or hemorrhagic
at the chronic phase (< 6 months)
Written informed consent
subject having a social insurance
Subject who consent to complete all the study's experiments

Healthy controls group:

Man or Woman
Age 18-80y
No history of neurological or psychiatric disease.

Exclusion criteria

Stroke group

Subject who is unable to consent (due to dementia, severe aphasia, psychiatric disorder...)
History of other neurologic disorders
Significant le vel of depression or anxiety, assessed by the STAI and the BDI questionnaires
Non corrected visual loss
Subjects suffering from visual neglect (assessed by the Bells Test and a bisection test (20mm)
contra-indications to MRI
pregnant or breastfeeding woman
Women of childbearing age without effective contraception

Healthy controls group

Subject who is unable to consent (due to dementia, severe aphasia, psychiatric disorder...)
History of neurologic disorders
Significant level of depression or anxiety, assessed by the STAI and the BDI questionnaires
Non-corrected visual loss
contra-indications to MRI
pregnant or breastfeeding woman
Women of childbearing age without effective contraception