Neural Correlates of Acute Pain Dynamics

Northwestern University

Status and phase: Completed; Phase 2

Conditions: Pain

Treatments: Drug: Methylphenidate; Drug: Placebo

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT05669924

STU00213557

Details and patient eligibility

About

This work aims to study the neural correlates and determinants of pain dynamics related to changes in a noxious stimulus.

Enrollment: 40 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Exclusion criteria

• Pregnant
• History of chronic pain
• History of neurological diagnosis
• History of psychiatric diagnosis

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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40 participants in 2 patient groups, including a placebo group

Methylphenidate

Experimental group

Treatment:

Drug: Methylphenidate

Placebo

Placebo Comparator group

Treatment:

Drug: Placebo