Neural Correlates of Real World Spatial Navigation in Humans

University of California, Los Angeles (UCLA)

Status: Enrolling

Conditions: Memory, Delayed

Treatments: Device: Deep Brain Stimulation

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04874220

20-001459

Details and patient eligibility

About

The purpose of this study is to understand the neural mechanisms that support real world spatial navigation in humans using deep brain recordings and stimulation during virtual reality (VR), augmented reality, and real world memory tasks. We will determine the cognitive (i.e., memory) and behavioral (i.e., body, head, eye position and movement) factors that modulate deep brain activity and the consequent effects of memory-enhancing deep brain stimulation.

Enrollment: 70 estimated patients

Sex: All

Ages: 12 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 12 years of age or older and has undergone RNS system placement
• Willing to provide informed consent and participate the study
• Ability to read and write English fluently

Exclusion criteria

• Unwilling to provide informed consent

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Double Blind