Neural Correlates of Stress Reduction

Mass General Brigham

Status: Completed

Conditions: Emotional Stress; Psychological Stress; Life Stress; Social Stress; Stress

Treatments: Behavioral: Stress Reduction

Study type: Interventional

Funder types: Other

Identifiers

NCT01488422

AT006344

Details and patient eligibility

About

This study will identify neural mechanisms associated with changes in emotion regulation following participation in stress reduction programs.

Enrollment: 140 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-50 years of age
• Right-handed
• Stressed

Exclusion criteria

• Lifetime history of schizophrenia or psychosis
• Psychiatric illness
• History of seizure or significant head trauma
• Use of psychotropic medications
• Metallic implants or devices contraindicating magnetic resonance imaging
• Claustrophobia
• Pregnancy

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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140 participants in 2 patient groups

Group 1

Active Comparator group

Description:

Both groups will receive stress reduction materials. We expect both groups to achieve similar amounts of stress reduction, but to use different brain regions to do so.

Treatment:

Behavioral: Stress Reduction

Group 2

Active Comparator group

Description:

Both groups will receive stress reduction materials. We expect both groups to achieve similar amounts of stress reduction, but to use different brain regions to do so.

Treatment:

Behavioral: Stress Reduction