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Neural Development of Deductive Reasoning (NEUREAS)

Civil Hospices of Lyon logo

Civil Hospices of Lyon

Status

Unknown

Conditions

Healthy Volunteers

Treatments

Other: fMRI scanning

Study type

Interventional

Funder types

Other

Identifiers

NCT02763657
2012.767

Details and patient eligibility

About

Children's understanding of linear-order (e.g., Dan is taller than Lisa, Lisa is taller than Jess) and set-inclusion (i.e., All tulips are flowers, All flowers are plants) relationships is critical for the acquisition of deductive reasoning, that is, the ability to reach logically valid conclusions from given premises. Behavioral and neuroimaging studies in adults suggest processing differences between these relations: While arguments that involve linear-orders may be preferentially associated with spatial processing, arguments that involve set-inclusions may be preferentially associated with verbal processing. In this study, we use functional magnetic resonance imaging to investigate how and when these processing differences appear in children from 8 to 14.

Enrollment

60 estimated patients

Sex

All

Ages

8 to 14 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Right-handed
  • Affiliated to the French social security
  • Whose parents gave informed consent

Exclusion criteria

  • Neurological disorders
  • Psychiatric disorders
  • Birth complications requiring admission into neonatal intensive care unit
  • Medication affecting central nervous system processing
  • Significant hearing impairment
  • Uncorrected visual impairment
  • Non-native English speaker
  • Contraindications for MRI

Trial design

Primary purpose

Basic Science

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

60 participants in 1 patient group

Brain activity during reasoning
Experimental group
Treatment:
Other: fMRI scanning

Trial contacts and locations

1

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Central trial contact

Justine EPINAT, CRA; Christian SCHEIBER, Pr, MD

Data sourced from clinicaltrials.gov

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