Neural Mechanism of Cortisol Awakening Response Suppression Effect on Human High-order and Social Cognitions (NMCARSEHHSC)

qinshaozheng

Status: Completed

Conditions: Healthy

Treatments: Drug: Vitamin C; Drug: Dexamethasone

Study type: Interventional

Funder types: Other

Identifiers

NCT02799134

ICBIR_A_0098_002

Details and patient eligibility

About

CAR is short for cortisol awakening response. The neural mechanism of CAR effect on high-order cognition and social cognition is less known...

Enrollment: 67 patients

Sex: Male

Ages: 18 to 26 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy college students.

Exclusion criteria

• Current or history of psychiatric or neurological illness.
• Current use of any medications.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Triple Blind

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67 participants in 3 patient groups, including a placebo group

group1

Experimental group

Description:

take Dexamethasone at 22:00 on the first day, 0.5mg

Treatment:

Drug: Dexamethasone

group2

Placebo Comparator group

Description:

take Vitamin C at 22:00 on the first day, 0.5mg

Treatment:

Drug: Vitamin C

group3

Other group

Description:

take Dexamethasone at 15:00 on the second day, 0.5mg

Treatment:

Drug: Dexamethasone