Neural Mechanisms of Cognitive Assessment and Rehabilitation for Cognitive Decline

National Research Center for Rehabilitation Technical Aids

Status: Enrolling

Conditions: Aging; Mild Cognitive Impairment (MCI); Healthy; Subjective Cognitive Decline (SCD)

Treatments: Combination Product: multi-modal targeted intervention (e.g., cognitive training, exercise, games)

Study type: Interventional

Funder types: Other

Identifiers

NCT05014893

201900045

Details and patient eligibility

About

This study investigates the neural mechanisms of cognitive function decline, cognitive assessment methods for subjects with mild cognitive dysfunction (Mild cognitive impairment, MCI, or cognitive decline milder than MCI), and the approaches used to improve and restore cognitive function.

Full description

Cognitive assessment tools are used to assess cognitive function of subjects in different cities. Functional and structural MRI and EEG are applied to investigate the neural mechanisms of cognitive function decline and effects of methods to improve and restore cognitive function.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults being able to walk at least a block, and
• Adults with subjective cognitive decline (SCD), or
• Adults with mild cognitive impairment (MCI), or
• Adults with normal cognitive function

Exclusion criteria

• Clinical diagnosis of dementia
• Adults who cannot follow the protocal

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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100 participants in 2 patient groups

Control

No Intervention group

Description:

Control group, without specific treatments

Cognitive training

Experimental group

Description:

This group receives treatments to improve cognitive function.

Treatment:

Combination Product: multi-modal targeted intervention (e.g., cognitive training, exercise, games)