Neural Mechanisms of Decision Making in Hoarding Disorder (LOSS)

Stanford University

Status: Active, not recruiting

Conditions: Hoarding Disorder

Treatments: Device: MRI with fMRI frequency

Study type: Observational

Funder types: Other

Identifiers

NCT03487224

42327

Details and patient eligibility

About

The purpose of this study is to understand the neural mechanisms of decision making in hoarding disorder.

Full description

Hoarding disorder is a common and disabling disorder that represents a significant public health problem. This study aims to build on current research on decision making by examining these processes in hoarding disorder.

Enrollment: 25 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Identify inclusion criteria.

Inclusion criteria for participants diagnosed with HD:

1. ages 18-70
2. primary diagnosis of hoarding disorder
3. sufficient severity of hoarding symptoms
4. stable on psychotropic medications for 1 month prior to study enrollment
5. capacity to provide informed consent
6. ability to tolerate clinical study procedures

Inclusion criteria for healthy control participants:

1. ages 18-70
2. capacity to provide informed consent

Identify exclusion criteria.

Exclusion criteria for participants with HD:

1. psychiatric or medical conditions that make participation unsafe
2. pregnant or nursing females
3. concurrent use of any medications that might increase the risk of participation (e.g. drug interactions)
4. presence of metallic device or dental braces

Exclusion criteria for healthy control participants:

1. any current or lifetime psychiatric diagnosis
2. current or past use of psychotropic medication
3. pregnant or nursing females
4. major medical or neurological problem
5. presence of metallic device or dental braces

Trial design

25 participants in 2 patient groups

Hoarding Disorder

Description:

Adults diagnosed with Hoarding Disorder

Treatment:

Device: MRI with fMRI frequency

Healthy Controls

Description:

Adults without mental illness

Treatment:

Device: MRI with fMRI frequency